If it’s a single exit point, of course it makes even less sense than just using Tor exit relays. But you could use many different exit points.
It will make more sense if you have a fixed and limited set of identities you need to maintain. So, perhaps a few Whonix-Workstaions, one per identity, configured differently: some using just Tor exit relays, others add specific VPNs / proxies, some use JonDonym, one goes through a VPS. Maybe even add other OS VMs and configure them to connect through Whonix-Gateway if you can do that.
Then, you can use different browsers too, for example take 10 most common browsers settings and configure your browsers accordingly.
Naturally such a complex system will increase the chance for mistakes and misconfigurations, so that’s another thing to keep in mind.