I am building a laptop with physical isolation and hardware kill switches

What’s your goal? Personal machine or development, something re-usable by others?

Would be useful to explain at first use what that means or link to some definition.

Internet says it has Rockchip RK3288 - Wikipedia which is

an ARM architecture System on Chip (SoC) from Rockchip

What Debian platform is that? arm64, armel, armhf or something?

Sounds interesting.

You’re in good luck since only recently arm64 builds were fixed. See: Whonix Development News

Therefore seems feasible that Whonix could also be ported to a lot / most / all platforms that are supported by Debian.

search maybe:

site:debian.org ARM Cortex-A17

I am not convinced that this would be any useful. See:

Security-Focused Operating System Comparison as Base for Whonix

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