If VMs aren’t an option, are two physical computers an option? If so, you may be able to make one of them a Whonix-Gateway and one a Whonix-Workstation. You’ll probably want to read this page carefully to understand the limitations of this and see if it will work for you:
If two computers are not an option, avoiding a VM will be hard, since you really need the network card to be entirely isolated from the applications that you’re using. Otherwise you risk leaks. You can potentially use a VM workstation on a baremetal gateway, or vice versa (both of these are undocumented, and you’ll need to use hardware passthrough if the gateway is the VM which introduces a lot of complexity). If neither of those options work for you, there isn’t really much more that can be done with the tools Whonix and Kicksecure offer.
If you only need specific apps isolated so that they use Tor, oniux might be a better fit for your use case.