If its done correctly can be handled but for surely more complexity. Has an issue at the moment:
** Guix Package Manager tested on Debian 11 it wont show or run the installed application from guix #48796
Not possible even on Guix own distro:
** You cant delete system packages using guix package manager, instead you do it manually #47748.
in debian case you do it using apt but not guix.
Rest of guix issues can be found here:
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