Is it safe to activate USB?

I sometimes have to copy files onto the workstation.
I did this by adding a shared folder.
Copy via virtualbox tools does not work, I do not know why. (Is this deactivated?)

It would be easier if I could just plug a USB stick in and connect it to the workstation.
USB is deactivated by whonix.

Is it safe to activate USB?

USB: The short answer is, something to avoid, but not totally unsafe. See also:

For a longer answer about USB, see how and why Qubes handles the USB stack.

Copy via virtualbox tools does not work, I do not know why. (Is this deactivated?)
You mean clipboard sharing? If so, the answer is here: https://www.whonix.org/wiki/VirtualBox_Guest_Additions#Clipboard_Sharing